Final rule · 2026-20748

Schedules of Controlled Substances: Placement of O-Desmethyltramadol in Schedule I; Correction

On August 12, 2026, the Drug Enforcement Administration (DEA) published a temporary order placing O-desmethyltramadol (other names: O-DSMT; desmetramadol; 3-[(1R,2R)-2-[(dimethylamino)methyl]-1- hydroxycyclohexyl]phenol), including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers are possible, in schedule I of the Controlled Substances Act. DEA published this temporary order that specifically noted in the summary that the control of O-desmethyltramadol included its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers are possible, however inadvertently omitted the correct language that should have been included. This document corrects that error, adding the correct language.